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Updated: Aug 13, 2026

Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency
Published on: January 15, 2017
Nonreversed saphenous vein grafts for coronary artery bypass grafting
1Division of Cardiovascular and Thoracic Surgery, University of Minnesota Medical School, Minneapolis.
Insights
Nonreversed saphenous vein grafts in coronary artery bypass grafting (CABG) show a satisfactory 90% patency rate. This technique offers advantages like better size matching and fewer anastomoses, making it a recommended option for CABG procedures.
Area of Science:
- Cardiovascular Surgery
- Vascular Grafting
- Coronary Artery Bypass Grafting
Background:
- Saphenous vein grafts are commonly used in coronary artery bypass grafting (CABG).
- Understanding vein diameter variations and their impact on graft performance is crucial.
- Optimizing graft selection and technique can improve long-term outcomes.
Purpose of the Study:
- To evaluate the efficacy and outcomes of using nonreversed valvotomized saphenous vein grafts in CABG.
- To assess the patency rates and anatomical suitability of these grafts.
- To determine the advantages of this technique compared to traditional methods.
Main Methods:
- A retrospective analysis of 365 patients undergoing CABG between August 1985 and December 1988.
- Measurement of saphenous vein diameters at different anatomical levels (femoral, knee, ankle).
- Assessment of graft patency through postoperative angiograms and autopsy findings.
Main Results:
- A total of 1,310 grafts were implanted (3.6 per patient).
- Graft patency was 90% in 120 grafts assessed by angiography and 95.5% (43/45) in grafts examined at autopsy.
- Vein diameter ratios indicated significant tapering from the femoral to distal ends.
Conclusions:
- Nonreversed saphenous vein grafts are recommended for CABG due to satisfactory patency rates.
- This technique facilitates a large proximal anastomosis and utilizes natural vein bifurcations.
- Improved vein-coronary artery size matching and reduced need for proximal anastomoses are key benefits.
Abstract:
Between August 1985 and December 1988, valvotomized saphenous vein grafts were used in 365 patients undergoing coronary artery bypass grafting (CABG). In this operation, the femoral end of the vein is attached to the aorta and the pedal end is attached to the coronary artery. Vein diameters measured 8 +/- 2 mm at the femoral end, 4.5 +/- 1.2 mm at the knee level, and 3.5 +/- 1.3 mm at the ankle. Ratios between levels were as follows: knee to femoral end, 0.56, and ankle to femoral end, 0.43. The ratio of knee to femoral end was 0.42 in cases with vein midthigh bifurcation. There were 1,310 grafts implanted (3.6 per patient). In 341 patients, CABG alone was performed, and 24 patients had combined procedures: 11 had CABG with mitral valve replacement, 9 had CABG with aortic valve replacement, 2 had CABG with repair of postinfarct ventricular septal defect, and 2 had CABG with automatic defibrillator implantation. Follow-up (up to 3.5 years) was attained in 97% of patients. For various reasons, 34 patients had a second angiogram between 3 and 41 months postoperatively. Of 120 vein grafts, 108 (90%) were patent. At autopsy, 11 patients with 45 vein grafts had 43 patent and clean grafts and two thrombosed. Use of nonreversed saphenous vein for coronary bypass is recommended. It assures a large proximal anastomosis, natural vein bifurcations can be used with fewer proximal anastomoses, better vein-coronary artery size matching is obtained, and the patency rate is satisfactory.
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