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Related Experiment Videos

Tissue adhesive in bronchial closure.

J Eng1, S Sabanathan

  • 1Department of Thoracic Surgery, Bradford Royal Infirmary, England.

The Annals of Thoracic Surgery
|November 1, 1989
PubMed
Summary
This summary is machine-generated.

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N-butyl-2-cyanoacrylate effectively sealed bronchial stumps and anastomoses in pulmonary resections, preventing bronchopleural fistulas and stenosis. This tissue adhesive offers a safe and efficient alternative in thoracic surgery.

Area of Science:

  • Thoracic Surgery
  • Surgical Adhesives
  • Pulmonary Medicine

Background:

  • Bronchopleural fistula and stenosis are significant complications following pulmonary resections.
  • Traditional methods for bronchial stump closure and anastomosis may require extensive suturing and can lead to complications.
  • The need for effective and safe adjuncts in thoracic procedures is ongoing.

Purpose of the Study:

  • To evaluate the efficacy and safety of monomeric n-butyl-2-cyanoacrylate as a tissue adhesive in pulmonary resections.
  • To assess its role in preventing bronchopleural fistula and bronchial stenosis.
  • To determine its utility in strengthening bronchial stumps and aiding anastomotic closure.

Main Methods:

  • Monomeric n-butyl-2-cyanoacrylate was applied to 25 patients undergoing pulmonary resections.

Related Experiment Videos

  • Used to reinforce bronchial stumps after pneumonectomy (n=11).
  • Used to facilitate bronchial (n=13) and tracheal (n=1) anastomosis after sleeve resections.
  • Main Results:

    • No incidence of bronchopleural fistula was observed in any patient.
    • No bronchial stenosis occurred postoperatively.
    • Bronchial anastomosis required fewer sutures (four apposing sutures) with airtight closure ensured by the adhesive.

    Conclusions:

    • Monomeric n-butyl-2-cyanoacrylate is an effective agent for preventing fistula formation after bronchial resections.
    • Its use simplifies anastomosis and ensures airtight closure, reducing suture requirements.
    • The adhesive obviates the need for pedicled pleural flaps, preserving pleural integrity for postoperative analgesia.