[Prophylactic treatment of episodic cluster headaches with methysergide and prednisone]

In two consecutive series of 25 cases each suffering from episodic cluster headache, one of the clusters was treated prophylactically in the first series with methysergide and in the other with prednisone. The duration of the clusters under treatment was similar in both series. The results of our study suggest that neither the methysergide nor the prednisone were able to shorten the duration of clusters.