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Charting a Course for Precision Oncology.
1US Department of Energy, Washington, DC, USA.
Clinical Pharmacology and Therapeutics
|February 10, 2017
Summary
Scientific fields are evolving towards large-scale, collaborative team science due to increasing complexity and costs. This transformation is crucial for advancements in areas like precision medicine, mirroring trends seen in particle physics.
Area of Science:
- Evolution of scientific research methodologies.
- Interdisciplinary collaboration and team science.
Background:
- Historical shifts in scientific research organization, from small-scale to large, cooperative efforts.
- Increasing complexity, costs, and skill requirements driving scientific reorganization.
- Examples include particle physics' evolution from single-investigator to international centers.
Purpose of the Study:
- To examine the trend of scientific fields reorganizing towards team-based approaches.
- To highlight the necessity of new organizational principles for scientific progress.
- To position precision medicine within this broader scientific transformation.
Main Methods:
- Analysis of historical trends in scientific research organization.
- Case study of particle physics evolution.
- Examination of current developments in computational sciences and precision medicine.
Main Results:
- Scientific fields are increasingly adopting large-scale, collaborative team structures.
- Advancements like the Higgs boson discovery underscore the success of team science.
- Precision medicine requires similar organizational shifts to achieve progress.
Conclusions:
- The trend towards team science is a necessary adaptation for complex research fields.
- Precision medicine must embrace new organizational models for significant breakthroughs.
- Initiatives like the Cancer Moonshot exemplify the potential of directed, collaborative efforts.
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