Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Complex microphthalmos.

A H Weiss1, B G Kousseff, E A Ross

  • 1Department of Ophthalmology, University of South Florida Medical Center, Tampa 33612.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|November 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A new malaria vector in Africa: Predicting the expansion range of <i>Anopheles stephensi</i> and identifying the urban populations at risk.

Proceedings of the National Academy of Sciences of the United States of America·2020
Same author

A multi-stop time-of-flight spectrometer for the measurement of positron annihilation-induced electrons in coincidence with the Doppler-shifted annihilation gamma photon.

The Review of scientific instruments·2020
Same author

Auger electron emission initiated by the creation of valence-band holes in graphene by positron annihilation.

Nature communications·2017
Same author

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.

Annals of the rheumatic diseases·2016
Same author

Time of flight spectrometer for background-free positron annihilation induced Auger electron spectroscopy.

The Review of scientific instruments·2016
Same author

Esophageal motility in eosinophilic esophagitis.

Revista de gastroenterologia de Mexico·2015
Same journal

The economics of the initial preventive physical examination in medicare-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

December 2011 archives web quiz winner.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

About this journal.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

In memoriam: goodwin m. Breinin, MD (1918-2011).

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
See all related articles

Complex microphthalmos, a congenital condition, results in a smaller eye size. This study suggests inadequate secondary vitreous production causes this condition, impacting posterior eye segment development.

Area of Science:

  • Ophthalmology
  • Developmental Biology
  • Genetics

Background:

  • Complex microphthalmos is characterized by a malformed globe with significantly reduced axial length.
  • Various ocular malformations can be associated with complex microphthalmos.

Purpose of the Study:

  • To investigate the underlying causes and developmental characteristics of complex microphthalmos.
  • To determine the etiological factors contributing to the reduced axial length in complex microphthalmos.

Main Methods:

  • Recruited 40 patients diagnosed with complex microphthalmos.
  • Measured total axial length, anterior and posterior segment lengths, corneal diameter, and lens and corneal power.
  • Analyzed the correlation between different ocular measurements and identified associated malformations.

Related Experiment Videos

Main Results:

  • Complex microphthalmos is a congenital condition with postnatal growth similar to normal eyes.
  • Posterior segment length was disproportionately reduced in all patients, while anterior segment length was mostly normal.
  • Corneal diameter significantly correlated with total axial length, and increased lens and corneal power were observed.

Conclusions:

  • Inadequate production of secondary vitreous is proposed as the primary cause of complex microphthalmos.
  • The reduction in posterior segment size is attributed to insufficient secondary vitreous development.
  • Specific ocular malformations may influence secondary vitreous production, contributing to microphthalmos.