Related Experiment Video

Updated: Mar 7, 2026

Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model
05:38

Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model

Published on: January 7, 2019

19.1K

DJ-1 and Parkin Modulate Dopamine-dependent Behavior and Inhibit MPTP-induced Nigral Dopamine Neuron Loss in Mice

Jean-Charles Paterna, Andreas Leng, Elisabeth Weber

    Molecular Therapy : the Journal of the American Society of Gene Therapy
    |February 10, 2017
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease
    08:09

    Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

    Published on: January 7, 2014

    8.0K
    Murine Model for Parkinson's Disease: from 6-OH Dopamine Lesion to Behavioral Test
    08:06

    Murine Model for Parkinson's Disease: from 6-OH Dopamine Lesion to Behavioral Test

    Published on: January 15, 2010

    32.5K

    Related Experiment Videos

    Last Updated: Mar 7, 2026

    Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model
    05:38

    Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model

    Published on: January 7, 2019

    19.1K
    Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease
    08:09

    Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

    Published on: January 7, 2014

    8.0K
    Murine Model for Parkinson's Disease: from 6-OH Dopamine Lesion to Behavioral Test
    08:06

    Murine Model for Parkinson's Disease: from 6-OH Dopamine Lesion to Behavioral Test

    Published on: January 15, 2010

    32.5K

    Related Concept Videos

    Parkinson's Disease: Treatment01:24

    Parkinson's Disease: Treatment

    1.3K
    Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
    Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
    1.3K

    Articles linked to this work by shared authors, journal, and citation graph.

    Post-COVID-19 Condition in Swiss Healthcare: Disparities in Access, Delays in Care, and Patient Burden.

    Healthcare (Basel, Switzerland)·2026

    Abundance-biased codon diversification prevents recombination in AAV production and ensures robust in vivo expression of functional FRET sensors.

    Communications biology·2025

    Elranatamab for Relapsed/Refractory Multiple Myeloma With Severe Renal Impairment Requiring Hemodialysis.

    Hematological oncology·2025

    Activation of toll-like receptor 2 promotes the expression of inflammatory mediators and cell proliferation of human polycystic kidney disease cells.

    Cellular signalling·2025

    Key Challenges for In Vitro Testing of Tobacco Products for Regulatory Applications: Recommendations for the In Vitro Mouse Lymphoma Assay.

    Alternatives to laboratory animals : ATLA·2023

    Driving the quadricyclane-to-norbornadiene isomerization by charge separation with perylenediimide as electron acceptor.

    Chemical science·2023

    IL-12-producing iPSC-derived antigen-presenting cells enhance antitumor immunity and enable off-the-shelf immunotherapy.

    Molecular therapy : the journal of the American Society of Gene Therapy·2026

    A natural compound derivative targeting HADHA disrupts mitochondrial homeostasis and suppresses renal cell carcinoma.

    Molecular therapy : the journal of the American Society of Gene Therapy·2026

    Lentiviral gene therapy corrects the metabolic and immune abnormalities in purine nucleoside phosphorylase-deficient mice.

    Molecular therapy : the journal of the American Society of Gene Therapy·2026

    Beyond Excitotoxicity: Glutamate-Independent Mechanisms Underlie Noise-Induced Synaptopathy and Compromise Gene Therapy for Hereditary Deafness.

    Molecular therapy : the journal of the American Society of Gene Therapy·2026

    The allogeneic eDN70(-) CAR-T Cells Without TCR or MHC Editing Exhibit Enhanced Persistence and Function.

    Molecular therapy : the journal of the American Society of Gene Therapy·2026

    Reprogramming immunosuppressive TMEs with Salmonella-delivered sialidase and COX-2 blockade synergistically enhances cancer immunotherapy.

    Molecular therapy : the journal of the American Society of Gene Therapy·2026

    Efficacy analysis and adverse event management of selinexor in the treatment of relapsed/refractory multiple myeloma.

    Frontiers in medicine·2026

    Case Report: Panic attacks after tirzepatide injection in two female patients with recurrent depressive disorder.

    Frontiers in drug safety and regulation·2026

    Individualized dosing in the precision medicine era: a narrative review.

    Frontiers in pharmacology·2026

    Targeting the Parkinson's disease interactome: a systems pharmacology and molecular dynamics investigation unveils Berberis aristata-derived phytoconstituents as potential modulators of tyrosine hydroxylase and p53: a systems and molecular dynamics investigation.

    In silico pharmacology·2026

    Transcriptomic insights into loperamide-induced gastric dysmotility: RNA-seq analysis of a mouse model.

    Frontiers in physiology·2026

    Beyond pharmacology: The mediating role of expectations in the experience of side effects in anxious patients treated with secukinumab.

    Brain, behavior, & immunity - health·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us