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Published on: October 24, 2025
Is the superior laryngeal nerve really safe when using harmonic focus in total thyroidectomy? A prospective
Kemal Arslan1, Bulent Erenoglu1, Osman Dogru1
1Department of General Surgery, Sağlık Bilimleri University, Konya Training and Research Hospital, Turkey.
Harmonic focus (HF) in total thyroidectomy significantly reduces operative time compared to conventional ligation (CL). This study found HF to be as safe as CL, with similar complication rates and superior laryngeal nerve function preservation.
Area of Science:
- Endocrine Surgery
- Surgical Technology
- Thyroid Procedures
Background:
- Harmonic focus (HF) was developed to potentially decrease operative time and complications in thyroid surgery.
- Evaluating novel surgical techniques is crucial for improving patient outcomes.
Purpose of the Study:
- To compare the function of the superior laryngeal nerve and the incidence of postoperative complications between total thyroidectomies performed with HF and conventional ligation (CL).
Main Methods:
- A randomized, single-center, single-blinded study involving patients aged 18 years or older undergoing total thyroidectomy.
- Utilized an ultrasonic dissector for coagulation and cutting in the HF group, versus standard techniques in the CL group.
- Collected and analyzed demographic, surgical, and complication data.
Main Results:
- Operative time was significantly shorter in the HF group compared to the CL group (p=0.01).
- No significant differences were observed in drain necessity, drainage duration, hospitalization duration, or overall postoperative complication rates between the groups (p>0.05).
- Nerve palsy rates were comparable between the HF and CL groups at 6 months.
Conclusions:
- Harmonic focus (HF) is demonstrated to be as safe as the conventional ligation (CL) technique for total thyroidectomy.
- This study is the first to specifically compare these techniques regarding external branch of the superior laryngeal nerve function using laryngostroboscopy.
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