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sfinx: an R package for the elimination of false positives from affinity purification-mass spectrometry datasets
Kevin Titeca1,2, Pieter Meysman3,4, Kris Laukens3,4
1VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium.
Summary:
We describe sfinx, an R package providing access to the straightforward filtering index (SFINX) for the separation of true positive from false positive protein interactions in affinity purification - mass spectrometry datasets. This package maintains the reliability and user-friendliness of the SFINX web site interface but is faster, unlimited in input size, and can be run locally within R.
Availability And Implementation:
The sfinx R package is available for download at the comprehensive R archive network (CRAN) https://cran.r-project.org/web/packages/sfinx/ under the Apache License 2.0.
Contact:
sven.eyckerman@vib-ugent.be or kevin.titeca@gmail.com.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
