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Updated: May 11, 2026

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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Published on: September 20, 2016
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Next-Generation Sequencing of Circulating Tumor DNA for Early Cancer Detection
Alexander M Aravanis1, Mark Lee1, Richard D Klausner1
1GRAIL, Menlo Park, CA 94402, USA.
Cell
|February 11, 2017
Abstract:
Curative therapies are most successful when cancer is diagnosed and treated at an early stage. We advocate that technological advances in next-generation sequencing of circulating, tumor-derived nucleic acids hold promise for addressing the challenge of developing safe and effective cancer screening tests.

