Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

1.8K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.8K
DNA Microarrays02:34

DNA Microarrays

21.7K
Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
21.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of the bacterial community of the human upper respiratory tract in patients affected by Covid-19.

Genetics and molecular biology·2026
Same author

Same Sentences, Different Grammars, Different Brain Responses?: An MEG Study on Case and Agreement Encoding in Hindi and Nepali Split-Ergative Structures.

Neurobiology of language (Cambridge, Mass.)·2026
Same author

Large variations in analgesic consumption patterns in youth elite athletes: a 28-week prospective cohort study.

Journal of science and medicine in sport·2026
Same author

The genome sequence of the açaí berry (<i>Euterpe oleracea</i> Mart.) and RNA-Seq analysis of the fruit ripening.

Genome·2026
Same author

General-purpose topology-aware embedding of tumor phylogenetic trees with graph neural networks.

Bioinformatics advances·2026
Same author

Surface Passivation of HgTe Nanocrystals Enabling E<sub>G</sub>/2 Open-Circuit Voltage and Their Coupling to Dielectric Cavity for Narrow Detection.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

Updates and validation of the Compi RNA-seq pipeline with a case study in Alzheimer's disease.

Journal of integrative bioinformatics·2026
Same journal

Fragment-level FAIRness: annotating scientific data and its provenance using data fragment selectors.

Journal of integrative bioinformatics·2026
Same journal

Integrating cross-omics research through FAIR Digital Objects with DataPLANT.

Journal of integrative bioinformatics·2026
Same journal

Pheno-App 2.0 - a mobile app for collecting phenotypic data in plant research.

Journal of integrative bioinformatics·2026
Same journal

Evolving bioinformatics services - the journey of KPI metrics with Scorpion.

Journal of integrative bioinformatics·2026
Same journal

The community engagement and empowerment cycle: FAIRagro's framework to foster cultural change towards FAIR RDM practices in agrosystem science and beyond.

Journal of integrative bioinformatics·2026
See all related articles

Related Experiment Video

Updated: Mar 7, 2026

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
14:56

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies

Published on: May 6, 2022

5.3K

Jllumina - A comprehensive Java-based API for statistical Illumina Infinium HumanMethylation450 and MethylationEPIC

Diogo Almeida, Ida Skov, Jesper Lund

    Journal of Integrative Bioinformatics
    |February 11, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Jllumina is a new Java library for processing Illumina methylation array data. It simplifies epigenome-wide association studies (EWAS) by providing efficient tools for raw data manipulation and statistical analysis.

    More Related Videos

    Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
    13:47

    Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

    Published on: February 24, 2015

    26.5K
    Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
    07:50

    Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer

    Published on: September 18, 2020

    6.2K

    Related Experiment Videos

    Last Updated: Mar 7, 2026

    Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
    14:56

    Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies

    Published on: May 6, 2022

    5.3K
    Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
    13:47

    Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

    Published on: February 24, 2015

    26.5K
    Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
    07:50

    Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer

    Published on: September 18, 2020

    6.2K

    Area of Science:

    • Epigenetics
    • Bioinformatics
    • Computational Biology

    Background:

    • Epigenome-wide association studies (EWAS) link DNA methylation to diseases.
    • Illumina's HumanMethylation450 and MethylationEPIC BeadChips are popular for EWAS.
    • Existing R-based solutions for raw data processing are limited for certain applications.

    Purpose of the Study:

    • To develop an open-source Java library for processing Illumina methylation array data.
    • To provide efficient tools for raw data manipulation and statistical analysis in EWAS.
    • To support the development of new bioinformatics tools and pipelines.

    Main Methods:

    • Developed Jllumina, an open-source Java library.
    • Implemented functions for reading and preprocessing raw Illumina methylation data.
    • Included statistical assessment, permutation tests, and differential methylation analysis.

    Main Results:

    • Jllumina supports Illumina Infinium HumanMethylation450 and MethylationEPIC BeadChip data.
    • The library is fully parallelizable, optimizing runtime and memory consumption.
    • Provides comprehensive Java functions for EWAS downstream analysis.

    Conclusions:

    • Jllumina addresses the need for efficient, high-quality data processing for Illumina methylation arrays.
    • Facilitates the integration of EWAS data into web services and larger analytical frameworks.
    • Offers a valuable resource for researchers conducting epigenome-wide association studies.