Cytotoxicity of mouse serum and peritoneal fluid for Ascaris suum infective larvae

Serum from BALB/c mice infected with Ascaris suum resulted in 51Cr release from A. suum infective larvae during in vitro incubation. Peritoneal fluid from infected or noninfected BALB/c mice also produced in vitro release of 51Cr from A. suum larvae. 51Cr release did not occur when anti-A. suum serum or peritoneal fluid from infected or noninfected mice were heat-inactivated. Serum and peritoneal fluid from infected or noninfected AKR-C5 deficient mice did not generate 51Cr release from A. suum larvae.