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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Updated: Mar 7, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Published on: July 8, 2025

Trabeculectomy bleb-associated infections.

M Reza Razeghinejad¹, Shane J Havens¹, L Jay Katz²

¹Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska, USA.

Survey of Ophthalmology

|February 12, 2017

Summary

This summary is machine-generated.

Trabeculectomy surgery for glaucoma can lead to serious bleb-associated infections. This review examines risk factors and proposes diagnostic and treatment strategies for these infections.

Keywords:

bleb-associated Endophthalmitis blebitis trabeculectomy

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Area of Science:

Ophthalmology
Surgical Innovation

Background:

Trabeculectomy with antimetabolites is a primary glaucoma surgery for advanced disease.
Bleb-associated infections are a significant complication with poor prognosis.

Purpose of the Study:

To review risk factors for bleb-associated infections after trabeculectomy.
To propose a diagnostic and therapeutic approach for these infections.

Main Methods:

Comprehensive literature review of studies on trabeculectomy and bleb infections.
Analysis of factors including surgical technique, patient comorbidities, and bleb characteristics.

Main Results:

Identified surgical technique, conjunctival incision, ocular comorbidities, and medications as potential risk factors.
Highlighted the variable response to antimicrobial therapy.

Conclusions:

Understanding risk factors is crucial for preventing bleb infections.
A structured diagnostic and therapeutic approach is needed for managing bleb infections.