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Hyperbaric oxygenation for necrotizing (malignant) otitis externa.

A Shupak1, E Greenberg, R Hardoff

  • 1Department of Otolaryngology, Carmel Lady Davis Hospital, Haifa, Israel.

Archives of Otolaryngology--Head & Neck Surgery
|December 1, 1989
PubMed
Summary
This summary is machine-generated.

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Hyperbaric oxygenation effectively treated two patients with severe necrotizing otitis externa, even when antibiotics were reduced. This therapy offers a promising adjuvant treatment for this challenging infection.

Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Hyperbaric Medicine

Background:

  • Necrotizing otitis externa is a severe infection often requiring aggressive treatment.
  • Standard antibiotic therapy can be limited by side effects and resistance.
  • Complicated cases may involve facial nerve palsy and skull base involvement.

Observation:

  • Two patients with extensive NOE were treated with hyperbaric oxygenation (HBO).
  • Antibiotic regimens were modified due to adverse effects before HBO initiation.
  • The infections were active at the time HBO therapy commenced.

Findings:

  • Hyperbaric oxygenation therapy led to complete resolution of NOE in both patients.
  • No recurrence of the necrotizing infection was observed post-treatment.

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  • HBO demonstrated efficacy even with reduced or withdrawn antibiotic support.

    • Implications:

    • HBO may be a valuable adjuvant therapy for refractory or complicated necrotizing otitis externa.
    • Understanding NOE pathogenesis and HBO mechanisms can guide treatment strategies.
    • Availability of therapeutic pressure chambers should prompt consideration of HBO for NOE.