Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bleeding time, blood groups and von Willebrand factor.

K M Caekebeke-Peerlinck1, T Koster, E Briët

  • 1Department of Haematology, University Hospital Leiden, The Netherlands.

British Journal of Haematology
|October 1, 1989
PubMed
Summary

People with blood group O have a longer bleeding time than those with other blood groups, regardless of sex, platelet count, or hematocrit. This finding was consistent across both Ivy and Simplate II bleeding time tests.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MR lymphangiography of lymphatic abnormalities in children and adults with Noonan syndrome.

Scientific reports·2022
Same author

A peculiar case of syphilis infection: The great imitator is on the rise.

IDCases·2022
Same author

The level and distribution of methyl-esters influence the impact of pectin on intestinal T cells, microbiota, and Ahr activation.

Carbohydrate polymers·2022
Same author

Ultrasound-guided needle positioning for nodal dynamic contrast-enhanced MR lymphangiography.

Scientific reports·2022
Same author

Complicated Carriage with Methicillin-Resistant Staphylococcus aureus: Evaluation of the Effectiveness of Decolonization Regimens Advised in the Dutch National Guideline.

Antimicrobial agents and chemotherapy·2021
Same author

Elastic compression stockings one year after DVT diagnosis: Who might discontinue?

Thrombosis research·2018

Area of Science:

  • Hematology
  • Blood Group Research
  • Hemostasis Studies

Background:

  • Bleeding time is a crucial indicator of primary hemostasis.
  • Blood group O is known to be associated with certain hemostatic differences.
  • Understanding variations in bleeding time is important for clinical assessment.

Purpose of the Study:

  • To compare bleeding times between individuals with blood group O and non-O blood groups.
  • To investigate potential factors influencing bleeding time differences, including von Willebrand factor levels.
  • To validate findings using two distinct bleeding time measurement techniques.

Main Methods:

  • Utilized Ivy and Simplate II techniques for bleeding time assessment in healthy volunteers.
  • Compared bleeding times between blood group O and non-O cohorts.

Related Experiment Videos

  • Analyzed data considering sex ratio, platelet count, and hematocrit.
  • Measured von Willebrand factor levels across all participants.

    • Main Results:

    • A statistically significant increase in bleeding time was observed in individuals with blood group O compared to non-O groups using both methods.
    • This difference in bleeding time was independent of sex, platelet count, and hematocrit.
    • No correlation was found between von Willebrand factor levels and bleeding time, despite lower mean levels in blood group O.

    Conclusions:

    • Blood group O is associated with prolonged bleeding times in healthy individuals.
    • The observed difference in bleeding time is not explained by variations in sex, platelet count, hematocrit, or von Willebrand factor levels.
    • Further research may be needed to elucidate the precise mechanisms behind blood group-related hemostatic variations.