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Streptococcus Pneumoniae Intracranial Abscess and Post-Infectious Vasculitis

Alexandra Lucas1, Ko Ko Maung2, Ryan Ratts3

  • 1Geisel School of Medicine at Dartmouth , Hanover, NH.

Infectious Disease Reports
|February 14, 2017
PubMed

Insights

This case report details a rare instance of post-infectious vasculitis following Streptococcus pneumoniae infection. It highlights potential severe complications and treatment limitations for invasive pneumococcal disease.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Vascular Medicine

Background:

  • Intracranial abscesses are uncommon sequelae of Streptococcus pneumoniae infections.
  • Post-infectious vasculitis is a rare but serious complication of infections.
  • Invasive pneumococcal disease can lead to severe neurological complications.

Observation:

  • A 48-year-old male, post-splenectomy, presented with a complex S. pneumoniae infection.
  • The infection progressed from otitis media to mastoiditis, osteomyelitis, meningitis, and intracranial abscess.
  • The patient subsequently developed post-infectious vasculitis.

Findings:

  • This is the first reported case of post-infectious vasculitis in a patient with an intracranial abscess due to S. pneumoniae.
  • The case underscores the potential for severe, multi-systemic complications from invasive pneumococcal infections.
  • The clinical course highlights the challenges in managing invasive S. pneumoniae infections and their sequelae.

Implications:

  • Clinicians should maintain a high index of suspicion for vasculitis in patients with invasive S. pneumoniae infections, especially with neurological involvement.
  • Awareness of these potential adverse outcomes is crucial for timely diagnosis and management.
  • The case may prompt further investigation into the mechanisms and management strategies for post-infectious vasculitis secondary to pneumococcal infections.
Keywords:
intracranial abscesspost-infectious vasculitisstreptococcus pneumoniae

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