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Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
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Zika virus: A pandemic in progress.

Sankalp Yadav1, Gautam Rawal2, Mudit Baxi3

  • 1General Duty Medical Officer-II, Department of Medicine & TB, Chest Clinic Moti Nagar, North Delhi Municipal Corporation, New Delhi, India.

Journal of Translational Internal Medicine
|February 14, 2017
PubMed
Summary

Emerging Zika virus infections pose a global health threat. This paper reviews the virus, known since 1947, amid a lack of clear guidelines and treatments.

Keywords:
French PolynesiaZika virusarbovirusesdiagnosisemerging diseaseserumviruses

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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • The world faces increasing emerging infectious diseases.
  • The recent Zika virus outbreak has caused significant global concern, prompting a World Health Organization (WHO) emergency declaration.
  • Limited scientific literature and a lack of established clinical guidelines contribute to the challenges in managing outbreaks.

Purpose of the Study:

  • To provide an overview of the Zika virus, an emerging infectious agent.
  • To highlight the critical need for further research and development of medical countermeasures.
  • To inform healthcare professionals and policymakers about the current understanding of Zika virus.

Main Methods:

  • Literature review of existing studies on Zika virus.
  • Analysis of the impact of limited research on public health responses.
  • Examination of the implications of the absence of vaccines and antiviral treatments.

Main Results:

  • Zika virus, known since 1947, is an emerging threat with significant public health implications.
  • The scarcity of research has led to inadequate guidelines for controlling Zika virus transmission and management.
  • The lack of a clinical vaccine and effective antiviral drugs exacerbates the severity of the situation.

Conclusions:

  • Urgent need for enhanced research into Zika virus epidemiology, pathogenesis, and transmission.
  • Development of a Zika virus vaccine and antiviral therapies is crucial.
  • Strengthened global collaboration and information sharing are essential for managing emerging infectious diseases like Zika virus.