Related Experiment Video
Updated: Mar 7, 2026
09:56
Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles
Published on: August 2, 2016
15.6K
Glutathione-responsive paclitaxel dimer nanovesicles with high drug content
Qing Pei1, Xiuli Hu2, Junli Zhou1
1State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. xiez@ciac.ac.cn and University of Science and Technology of China, Hefei 230026, P. R. China.
Biomaterials Science
|February 14, 2017
Abstract:
Paclitaxel dimer-based nanovesicles, with an ultrahigh drug content, have been prepared through a nanoprecipitation method. The as-formed nanovesicles exhibit improved paclitaxel solubility, prominent colloid stability, GSH-triggered disassembly, effective cellular uptake and comparable cytotoxicity to Taxol.
