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Related Experiment Videos

GIST: Institutional Experience at SRMS-IMS, India.

Shubhanshu Gupta1, Keshri Amit1, Ashish Gupta2

  • 1Dept. of Surgical Oncology, SRMS-IMS, Bhojipura, Bareilly, India.

The Gulf Journal of Oncology
|February 14, 2017
PubMed
Summary

Gastro-Intestinal Stromal Tumors (GIST) are rare mesenchymal tumors. Early diagnosis and treatment, including surgery and Imatinib, improve survival rates for GIST patients.

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Area of Science:

  • Oncology
  • Gastroenterology
  • Surgical Pathology

Background:

  • Gastro-Intestinal Stromal Tumors (GIST) are malignant, non-epithelial, mesenchymal tumors of the digestive tract.
  • Diagnosis relies on immuno-histo-chemical analysis of resected or biopsied specimens.
  • Common presentations include abdominal lumps with or without gastrointestinal bleeding.

Purpose of the Study:

  • To present institutional experience with four GIST cases.
  • To highlight the diagnostic and management strategies for GIST.
  • To evaluate recurrence-free survival in managed GIST patients.

Main Methods:

  • Retrospective review of four GIST patients admitted to the Onco-Surgery Department.
  • Diagnosis confirmed via immuno-histo-chemical analysis.

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  • Management included surgery and/or Imatinib therapy based on disease stage.

    • Main Results:

    • All four patients presented with abdominal pain and gastrointestinal bleeding.
    • Diagnosis of GIST was confirmed in all cases.
    • Patients received stage-appropriate management, resulting in recurrence-free survival on follow-up.

    Conclusions:

    • GIST diagnosis requires immuno-histo-chemical analysis.
    • Timely surgical intervention and/or Imatinib therapy are crucial for improved outcomes.
    • Effective management strategies contribute to recurrence-free survival in GIST patients.