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Quantification of various APP-mRNA isoforms and epistasis in Lesch-Nyhan disease

Khue Vu Nguyen1, William L Nyhan2

  • 1Department of Medicine, Biochemical Genetics and Metabolism, The Mitochondrial and Metabolic Disease Center, School of Medicine, University of California, San Diego, Building CTF, Room C-103, 214 Dickinson Street, San Diego, CA, 92103-8467, USA; Department of Pediatrics, University of California, San Diego, School of Medicine, San Diego, La Jolla, CA, 92093, USA.

Neuroscience Letters
|February 14, 2017
PubMed

Keywords:
Amyloid precursor proteinEpigeneticsEpistasisKinetic methodLesch-Nyhan diseaseNeurodevelopmental and neurodegenerative disorders

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