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Abdominal Aortic Aneurysm Screening Reduces All-Cause Mortality: Make Screening Great Again
Hisato Takagi1, Tomo Ando2, Takuya Umemoto1
11 Department of Cardiovascular Surgery, Shizuoka Medical Center, Shizuoka, Japan.
Angiology
|February 15, 2017
Summary
Invitation to abdominal aortic aneurysm (AAA) screening for men aged 65+ significantly reduces all-cause and AAA-related mortality. Attending screening improves survival outcomes compared to non-attenders and non-invitees.
Area of Science:
- Vascular Surgery
- Public Health
- Epidemiology
Background:
- Abdominal aortic aneurysm (AAA) screening aims to reduce mortality.
- Long-term outcomes of AAA screening are crucial for evaluating its effectiveness.
Purpose of the Study:
- To update a meta-analysis on the longest follow-up results of AAA screening trials.
- To assess the impact of AAA screening invitation on all-cause and cause-specific mortality in older men.
Main Methods:
- Updated meta-analysis of 4 randomized controlled trials (RCTs).
- Included longest follow-up data (≥13 years).
- Analyzed data from men aged ≥64 years invited for AAA screening.
Main Results:
- Invitation to screening significantly reduced all-cause mortality (HR: 0.98; 95% CI: 0.96-0.99).
- Invitation significantly reduced AAA-related mortality (OR: 0.66; 95% CI: 0.47-0.93).
- Attenders had significantly lower all-cause and AAA-related mortality than non-attenders and non-invitees.
Conclusions:
- Invitation to AAA screening in men aged 64+ significantly reduces both all-cause and AAA-related mortality.
- Screening non-attenders showed higher all-cause and non-AAA-related mortality compared to non-invitees.
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