Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biofilms, bacteria and bladder catheters. A clinical study.

J W Ramsay1, A J Garnham, A B Mulhall

  • 1Department of Urology, St Bartholomew's Hospital, London.

British Journal of Urology
|October 1, 1989
PubMed
Summary

Biofilms frequently form on urethral catheters, regardless of material or duration of use. Antibiotic prophylaxis showed limited effectiveness in preventing biofilm development on these medical devices.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Medical negligence in urology: an untapped database.

Annals of the Royal College of Surgeons of England·2021
Same author

For debate: the short report - legal and ethical implications.

Annals of the Royal College of Surgeons of England·2021
Same author

Comment on Fomepizole as an adjunctive treatment in severe acetaminophen ingestions.

Clinical toxicology (Philadelphia, Pa.)·2020
Same author

Features reported after exposure to automatic dishwashing rinse aids.

Human & experimental toxicology·2020
Same author

Toxicity of traditional and soluble film automatic dishwashing tablets.

Human & experimental toxicology·2019
Same author

Foundation Year Doctors need more support.

The Medico-legal journal·2019

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Medical Devices

Background:

  • Catheter-associated urinary tract infections (CAUTIs) are a significant healthcare concern.
  • Biofilm formation on indwelling medical devices, particularly urethral catheters, is a primary mechanism for persistent infections.
  • Understanding biofilm dynamics on catheters is crucial for developing effective prevention strategies.

Purpose of the Study:

  • To investigate the prevalence of biofilm formation on urethral catheters.
  • To determine the relationship between biofilm microbial flora and bladder urine flora.
  • To assess the influence of catheter material, duration of use, and prophylactic antibiotics on biofilm development.

Main Methods:

  • Examination of 33 urethral catheters removed from patients.

Related Experiment Videos

  • Microbial analysis of biofilms on catheters and corresponding bladder urine samples.
  • Correlation analysis of biofilm presence with catheter material, indwelling time, and antibiotic prophylaxis.

    • Main Results:

    • Biofilms were detected on 16 out of 33 (48.5%) examined urethral catheters.
    • In 11 cases, the microbial composition of the catheter biofilm differed from that of the bladder urine.
    • Biofilm formation was observed across all tested catheter materials and was not influenced by the duration the catheter was in place.
    • Prophylactic antibiotics were used in 7 cases, with biofilms present on 2 of these catheters.

    Conclusions:

    • Biofilm formation on urethral catheters is a common occurrence.
    • Catheter biofilms can harbor distinct microbial communities compared to the urinary tract.
    • Current prophylactic antibiotic strategies appear to have limited efficacy in preventing catheter biofilm formation.