Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

6.0K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.0K
Skin Cancer01:30

Skin Cancer

6.4K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
6.4K
Reticular Dermis01:15

Reticular Dermis

5.3K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
5.3K
Papillary Dermis01:11

Papillary Dermis

6.5K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
6.5K
Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

1.1K
In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
1.1K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mapping the whispering gallery modes of a CaF<sub>2</sub> disk resonator with half-tapered fibers to estimate the fundamental mode volume.

Optics letters·2026
Same author

COPD exacerbation rates are higher in non-smoker patients in India.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2020
Same author

Use of Gla-100 in Special Situations.

The Journal of the Association of Physicians of India·2020
Same author

Pulmonary hamartoma.

The Indian journal of chest diseases & allied sciences·2014
Same author

Ambroxol hydrochloride in the management of idiopathic pulmonary fibrosis: Clinical trials are the need of the hour.

Lung India : official organ of Indian Chest Society·2014
Same author

Androgenetic alopecia and risk of coronary artery disease.

Indian dermatology online journal·2013
Same journal

Severe combined immunodeficiency (SCID) with pigmentary mosaicism: A coincidental occurrence in a child.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Agminated multifocal eruptive lobular capillary haemangiomas - An uncommon presentation.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Patch testing in India: Are we missing clinically relevant allergens?

Indian journal of dermatology, venereology and leprology·2026
Same journal

Double-loading technique for improved suspension retention on the recipient site in non-cultured epidermal cell suspension (NCES).

Indian journal of dermatology, venereology and leprology·2026
Same journal

Late-onset metastatic melanoma arising from a medium-sized congenital melanocytic naevus.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Custom-compounded glycine-proline jelly for ulcers in prolidase deficiency.

Indian journal of dermatology, venereology and leprology·2026
See all related articles

Related Experiment Video

Updated: Mar 7, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

21.0K

Scleredema-some Unusual Features.

S K Bhattacharya, Shyam Sundar, P R Gupta

    Indian Journal of Dermatology, Venereology and Leprology
    |February 15, 2017
    PubMed
    Summary
    This summary is machine-generated.

    This study reports two adult cases of scleredema, highlighting unusual electrocardiographic findings and a connection to pulmonary tuberculosis. These findings offer insights into scleredema

    More Related Videos

    Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
    05:39

    Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

    Published on: May 16, 2025

    784
    Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
    05:44

    Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

    Published on: June 10, 2025

    1.3K

    Related Experiment Videos

    Last Updated: Mar 7, 2026

    Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
    04:44

    Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

    Published on: June 16, 2020

    21.0K
    Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
    05:39

    Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

    Published on: May 16, 2025

    784
    Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
    05:44

    Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

    Published on: June 10, 2025

    1.3K

    Area of Science:

    • Cardiology
    • Dermatology
    • Infectious Diseases

    Background:

    • Scleredema is a rare connective tissue disorder characterized by diffuse, woody induration of the skin.
    • Adult-onset scleredema is uncommon, and its association with specific comorbidities requires further investigation.

    Observation:

    • Two adult patients presented with scleredema.
    • Both cases exhibited distinct and unusual electrocardiographic (ECG) abnormalities.
    • A significant association with active pulmonary tuberculosis was noted in both patients.

    Findings:

    • The electrocardiographic features observed were atypical for scleredema, suggesting potential cardiac involvement or secondary effects.
    • The co-occurrence of scleredema and pulmonary tuberculosis in these cases is noteworthy and warrants attention.
    • Review of relevant literature revealed limited data on similar presentations.

    Implications:

    • These cases underscore the importance of comprehensive cardiovascular evaluation in patients with scleredema, particularly when unusual ECG findings are present.
    • The association with pulmonary tuberculosis suggests a potential link or common underlying pathogenetic mechanism that merits further research.
    • Clinicians should consider screening for tuberculosis in patients presenting with scleredema, especially in the presence of cardiac symptoms or ECG changes.