Evaluation of Sub-population of Lymphocytes and Serum Immunoglobulins in Psoriasis

Sub-populations of lymphocytes and serum immunoglobulins were studied in 50 patients with psoriasis. Absolute T lymphocyte count was found to be significantly decreased. Though the null cells showed an increase, absolute B Lymphocyte count was normal. The decrease in T cells was found to be directly proportional to the extent of cutaneous involvement. Quantititive estimations of serum IgA and IgM were as IgO was found,to bc raised. The possible mechanism of these changes in psoriasis has been discussed.