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Intriguing Morphology of IgG/Lambda Secreting Myeloma Cells

Sreejesh Sreedharanunni1, Narender Kumar1, Neelam Varma1

  • 1Department of Hematology, Postgraduate Institute of Medical Education and Research, 5th Floor, Research Block A, Chandigarh, 160012 India.

Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion
|February 15, 2017
PubMed

Myeloma cells are known to show varied morphology and various types of nuclear or cytoplasmic inclusions. There are a few reports of myeloma with presence of pseudo-Gaucher type histiocytes; however myeloma cells itself resembling storage histiocytes is distinctly uncommon. We report images of plasma cells resembling storage cells from a case of IgG/lambda plasma cell myeloma. Hematopathologist must be aware of such varied morphology of plasma cells especially while dealing with extra medullary plasmacytomas.

Keywords:
AmyloidosisPlasma cell myelomaStorage disorder

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