Related Experiment Video
Updated: Mar 7, 2026

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
Primum non nocere-first do no harm. And then feed peanut
Kyla Jade Hildebrand1, Elissa Michele Abrams2, Timothy K Vander Leek3
1Program Director Clinical Immunology & Allergy Training Program, Faculty of Medicine, Department of Pediatrics, University of British Columbia, British Columbia Children's Hospital, 4480 Oak Street, Room 1C31B, Vancouver, BC V6H 3V4 Canada.
Abstract:
The Addendum Guidelines for the Prevention of Peanut Allergy in the United States-Report of the NIAID-Sponsored Expert Panel were developed to build on previous food allergy guidelines after several key studies demonstrated the benefit of early introduction of allergenic foods. These landmark studies including the Learning Early about Peanut (LEAP), LEAP-On and Enquiring about Tolerance trials created a paradigm shift in food allergy prevention. The "take home" messages of this guideline include that peanut should be introduced early in the first year of life, and for the majority of infants, peanut can be introduced at home. The only group of infants for which medical assessment is recommended is those with severe eczema, egg allergy or both. Here we summarize the Guideline recommendations, endorsed by the Canadian Society of Allergy and Clinical Immunology, and highlight important aspects relevant to Canadian practitioners.
Related Concept Videos
Allergic Reactions: Anaphylaxis
Allergic Reactions
Allergic Drug Reactions
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Prevention of Further Absorption of Poison
Drug Toxicity: Allergic Reactions

