Mental health status of people isolated due to Middle East Respiratory Syndrome
Related Experiment Video
Updated: Mar 7, 2026

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
Published on: November 11, 2022
Hyunsuk Jeong1, Hyeon Woo Yim1, Yeong-Jun Song2
1Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Objectives:
Isolation due to the management of infectious diseases is thought to affect mental health, but the effects are still unknown. We examined the prevalence of anxiety symptoms and anger in persons isolated during the Middle East Respiratory Syndrome (MERS) epidemic both at isolation period and at four to six months after release from isolation. We also determined risk factors associated with these symptoms at four to six months.
Methods:
Of 14,992 individuals isolated for 2-week due to having contact with MERS patients in 2015, when MERS was introduced to Korea, 1,692 individuals were included in this study. Anxiety symptoms were evaluated with the Generalized Anxiety Disorder 7-item scale and anger was assessed with the State-Trait Anger Expression Inventory at four to six months after release from isolation for MERS.
Results:
Of 1,692 who came in contact with MERS patients, 1,656 were not diagnosed with MERS. Among 1,656, anxiety symptoms showed 7.6% (95% confidence interval [CI], 6.3 to 8.9%) and feelings of anger were present in 16.6% (95% CI, 14.8 to 18.4%) during the isolation period. At four to six months after release from isolation, anxiety symptoms were observed in 3.0% (95%CI, 2.2 to 3.9%). Feelings of anger were present in 6.4% (95% CI, 5.2 to 7.6%). Risk factors for experiencing anxiety symptoms and anger at four to six months after release included symptoms related to MERS during isolation, inadequate supplies (food, clothes, accommodation), social networking activities (email, text, Internet), history of psychiatric illnesses, and financial loss.
Conclusions:
Mental health problems at four to six month after release from isolation might be prevented by providing mental health support to individuals with vulnerable mental health, and providing accurate information as well as appropriate supplies, including food, clothes, and accommodation.
Insights
Isolation during infectious disease outbreaks like MERS can impact mental health, with anxiety and anger persisting post-isolation. Addressing factors like inadequate supplies and providing mental health support can mitigate these long-term effects.
Area of Science:
- Epidemiology
- Public Health
- Mental Health Research
Background:
- Infectious disease isolation is suspected to impact mental health.
- Limited data exists on the long-term psychological effects of isolation during epidemics.
Purpose of the Study:
- To assess the prevalence of anxiety and anger in individuals isolated during the Middle East Respiratory Syndrome (MERS) epidemic.
- To identify risk factors for these mental health symptoms post-isolation.
Main Methods:
- A study included 1,692 individuals isolated for 2 weeks due to MERS contact in Korea, 2015.
- Anxiety and anger were evaluated using standardized scales (GAD-7, STAXI) 4-6 months after isolation release.
Main Results:
- During isolation, 7.6% experienced anxiety and 16.6% anger.
- Post-isolation (4-6 months), anxiety affected 3.0% and anger 6.4%.
- Risk factors included MERS symptoms during isolation, inadequate supplies, social networking, prior psychiatric issues, and financial loss.
Conclusions:
- Mental health issues post-isolation can be prevented.
- Providing mental health support, accurate information, and adequate supplies (food, clothing, accommodation) is crucial for vulnerable individuals.
Related Concept Videos
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Acute Respiratory Failure-IV
Physical Assessment of the Respiratory Tract I: Health History
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...

