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A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
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Follow-up MR imaging of PI-RADS 3 and PI-RADS 4 prostate lesions

Elke Hauth1, Horst Jaeger1, Horst Hohmuth2

  • 1Radiologische Praxis, Ulm, Germany.

Clinical Imaging
|February 16, 2017
PubMed
Abstract

Insights

Follow-up MRI is recommended for prostate PI-RADS 3 lesions. For PI-RADS 4 lesions with a negative initial biopsy, immediate repeat core biopsy is advised due to a high malignancy rate.

Area of Science:

  • Radiology
  • Oncology
  • Urology

Background:

  • Prostate cancer diagnosis relies on MRI and biopsy.
  • PI-RADS 3 lesions pose diagnostic uncertainty.
  • Negative biopsies in PI-RADS 4 lesions require further investigation.

Purpose of the Study:

  • To assess malignancy rates in PI-RADS 3 lesions without biopsy.
  • To evaluate malignancy rates in PI-RADS 4 lesions after negative initial biopsy.

Main Methods:

  • Follow-up MRI was performed on 72 patients.
  • 46 patients had PI-RADS 3 lesions.
  • 26 patients had PI-RADS 4 lesions with negative initial biopsy.

Main Results:

  • Malignancy rate for PI-RADS 3 lesions was 4%.
  • Malignancy rate for PI-RADS 4 lesions was 69%.

Conclusions:

  • Follow-up MRI is valuable for PI-RADS 3 lesions.
  • Repeat core biopsy is recommended for PI-RADS 4 lesions with negative initial results.
Keywords:
BiopsyDiagnosisFollow-upMR imagingProstate cancer

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