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Prevalence and patterns of congenital heart diseases in Africa: a systematic review and meta-analysis protocol

Aurel T Tankeu1, Jean Joel R Bigna2,3, Jobert Richie N Nansseu4,5

  • 1Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.

BMJ Open
|February 16, 2017
PubMed

Insights

This systematic review examines congenital heart diseases (CHD) in Africa. It aims to determine the prevalence and patterns of CHD to improve preventive strategies for children and adolescents.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Congenital heart diseases (CHD) are a significant cause of illness and death in young people in Africa.
  • Accurate epidemiological data are crucial for developing effective prevention and treatment strategies.
  • Existing data on CHD prevalence and patterns across Africa are limited.

Purpose of the Study:

  • To systematically review and meta-analyze the prevalence of CHD in Africa.
  • To identify the main patterns of congenital heart diseases across different African regions.
  • To provide a comprehensive epidemiological overview to inform public health interventions.

Main Methods:

  • Systematic review and meta-analysis of published studies (1986-2016).
  • Inclusion of cross-sectional, case-control, and cohort studies with echocardiographic confirmation of CHD.
  • Data extraction and bias assessment by two independent reviewers, with random-effects meta-analysis for prevalence estimation.

Main Results:

  • The review will synthesize prevalence data from diverse African populations.
  • Analysis will identify regional variations in CHD patterns.
  • Publication bias will be assessed using funnel plots and Egger's test.

Conclusions:

  • This study will establish a baseline for CHD burden in Africa.
  • Findings will guide targeted public health initiatives and resource allocation.
  • The results will be disseminated through a peer-reviewed publication.
Abstract

Keywords:
AfricaHeart defectscardiac malformation

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