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Updated: Mar 7, 2026

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Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
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Roux-en-Y Gastric Bypass
V E Fernández-Ruiz1, D Armero-Barranco2, J M Xandri-Graupera2
11 Murcia Healthcare Service, Murcia, Spain.
Biological Research for Nursing
|February 16, 2017
Summary
Roux-en-Y gastric bypass (RYGB) significantly improves metabolic syndrome and related disorders, with over 90% remission. However, RYGB did not show significant benefits for psychiatric comorbidities.
Area of Science:
- Bariatric surgery
- Metabolic disorders
- Psychiatric comorbidity
Background:
- Roux-en-Y gastric bypass (RYGB) is a leading bariatric surgery for obesity.
- RYGB demonstrates long-term efficacy for metabolic disorders.
- The study investigates RYGB's impact on metabolic syndrome and psychiatric conditions.
Purpose of the Study:
- To evaluate the effects of RYGB on metabolic syndrome (MS).
- To assess RYGB's influence on biochemical parameters linked to obesity comorbidities.
- To explore RYGB's impact on psychiatric comorbidities.
Main Methods:
- Observational retrospective cohort study.
- 146 patient records from January 2011 to January 2014.
- Metabolic and psychiatric data collected pre-surgery and at 3 and 9 months post-surgery.
Main Results:
- Significant reduction in most biochemical parameters post-RYGB.
- High-density lipoprotein cholesterol significantly increased post-RYGB.
- Over 90% remission of metabolic disorders; MS reduced to one patient at 9 months.
- No significant reduction in psychiatric comorbidity treatments.
Conclusions:
- RYGB is highly effective for treating metabolic syndrome and associated disorders.
- RYGB does not significantly improve psychiatric comorbidities.
- Further research may be needed for managing psychiatric conditions alongside RYGB.
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