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The Chronic Otitis Media Benefit Inventory (COMBI): Development and Validation of a Dynamic Quality of Life
John S Phillips1, Mark Haggard, Helen Spencer
1*Norfolk & Norwich University Hospital, Norwich, Norfolk †Multi-Centre Otitis Media Study Group, Department of Psychology, University of Cambridge, Cambridge ‡Ipswich Hospital, Ipswich, Suffolk, United Kingdom.
Objective:
This study introduces a change-oriented short-form health-related quality of life questionnaire suited to symptoms of adult chronic middle ear disease and its consequences, and describes its properties.
Study Design:
Two-centre prospective correlational study primarily for instrument development.
Setting:
Two otology secondary care centers in England.
Patients:
Fifty-two consecutive adult patients with active chronic otitis media undergoing surgery.
Methods:
The 12 items for the chronic otitis media benefit inventory (COMBI) were appraised chiefly for internal consistency of resulting score and for factor structure (exploratory factor analysis).
Results:
The internal consistency of the COMBI was high within our cohort of patients, with a Cronbach's alpha value of 0.907. The three-factor solution from factor analysis explaining 73.6% of the variance was readily interpretable in terms of the intended item content: changes in hearing, ear symptoms, and daily activities plus healthcare uptake.
Conclusions:
The COMBI has suitable properties for the dynamic assessment of active chronic otitis media. Initial psychometric appraisal confirms its suitability for early adoption to acquire more comprehensive large-sample information with it and on it, for future refinement and application.
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