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Microvalve-based bioprinting - process, bio-inks and applications.

Wei Long Ng¹, Jia Min Lee², Wai Yee Yeong²

¹Singapore Centre for 3D Printing (SC3DP), School of Mechanical and Aerospace Engineering, Nanyang Technological University (NTU), 50 Nanyang Avenue, Singapore 639798, Singapore. wyyeong@ntu.edu.sg and Singapore Institute of Manufacturing Technology (SIMTech), Agency for Science, Technology and Research, 73 Nanyang Drive, Singapore 637662.

Biomaterials Science

|February 16, 2017

Summary

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This summary is machine-generated.

This review explores microvalve bioprinting, a key technology for creating tissue constructs. It details drop-on-demand systems, bio-inks, and cell impacts for tissue engineering applications.

Area of Science:

Bioprinting and Tissue Engineering
Biomaterials Science
Regenerative Medicine

Background:

Bioprinting offers automated fabrication of complex bioengineered constructs.
Bio-inks with diverse biomaterials and cells enhance tissue and organ homology.
Reproducible manufacturing is crucial for advanced biomedical applications.

Purpose of the Study:

To provide a comprehensive review of microvalve-based bioprinting.
To analyze and compare different drop-on-demand bioprinting systems.
To highlight key considerations for microvalve bioprinting systems.

Main Methods:

Detailed analysis of microvalve bioprinting processes.
Evaluation of bio-ink properties and cellular components.

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Comparison of various drop-on-demand bioprinting technologies.

Main Results:

Microvalve bioprinting enables precise fabrication of in vitro tissue constructs.
Printing outcomes are significantly influenced by process, bio-ink, and cell types.
Drop-on-demand systems show promise for high-throughput screening and cell biology.

Conclusions:

Microvalve bioprinting is vital for tissue engineering and regenerative medicine.
Further development can transform this technology into essential tools.
Future directions focus on enhancing precision and application scope.