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Acupuncture for acute moderate thalamic hemorrhage: randomized controlled trial study protocol.

Chengwei Wang1, Chao You2, Lu Ma2

  • 1Department of Integrated Traditional and Western Medicine, West China Hospital, Sichuan University, Chengdu, China.

BMC Complementary and Alternative Medicine
|February 17, 2017
PubMed
Summary

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This randomized trial investigates if acupuncture improves outcomes for moderate thalamic hemorrhage (TH). Results will clarify acupuncture

Area of Science:

  • Neurology
  • Neurosurgery
  • Integrative Medicine

Background:

  • Thalamic hemorrhage (TH) is a severe neurological condition with significant morbidity and mortality.
  • Moderate TH (10-30 ml) constitutes over half of all cases, yet optimal treatment remains debated.
  • The efficacy of acupuncture for moderate TH is currently unclear.

Purpose of the Study:

  • To determine if acupuncture, as an adjunct to standard treatment, improves neurological outcomes in patients with moderate TH.
  • To evaluate the safety and effectiveness of acupuncture in different subgroups of moderate TH based on volume and location.

Main Methods:

  • A single-center, randomized, parallel-group, assessor-blinded clinical trial involving 488 patients with moderate TH.
  • Patients were assigned to eight groups: four study groups receiving acupuncture plus standard treatment, and four control groups receiving standard treatment alone.
Keywords:
AcupunctureIntracranial hemorrhageModerate thalamic hemorrhageRCT

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  • Primary outcome: Change in National Institutes of Health Stroke Scale scores at 30 and 90 days. Secondary outcomes include mortality, disability (modified Rankin Scale), need for surgery, and Glasgow Outcome Scale scores.

    • Main Results:

    • The study is designed to compare the rates of adverse events between acupuncture and control groups.
    • Primary and secondary outcomes will be analyzed to assess the impact of acupuncture on neurological recovery and functional status.

    Conclusions:

    • This trial aims to provide evidence on the effectiveness of acupuncture in improving neurological outcomes for patients with moderate thalamic hemorrhage.
    • Findings will inform clinical practice regarding the integration of acupuncture into the management of moderate TH.