Related Experiment Video
Updated: Mar 7, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
[Neurodevelopmental features of preterm infants at the corrected age of 1 year]
Mei Zhang1, Hong-Yan Qian, Xiao-Ni Kuang
1Department of Child Health Care, Changsha Maternal and Child Health Care Hospital, Changsha 410007, China. 1103549904@qq.com.
Insights
Preterm infants born earlier or with lower birth weight show poorer neurodevelopment. Complications like hyperbilirubinemia and birth asphyxia also negatively impact cognitive and motor skills in infants.
Area of Science:
- Neonatal care and developmental pediatrics.
Background:
- Preterm infants face risks for neurodevelopmental challenges.
- Early identification of risk factors is crucial for intervention.
Purpose of the Study:
- To assess neurodevelopment in preterm infants at 1 year corrected age.
- To examine the impact of gestational age, birth weight, and complications on infant neurodevelopment.
Main Methods:
- Retrospective study of hospitalized preterm infants' clinical and follow-up data.
- Neurodevelopmental assessment using Bayley Scales of Infant Development (BSID).
- Comparison of Mental Development Index (MDI) and Psychomotor Development Index (PDI) across different infant groups.
Main Results:
- Early preterm infants and those with low birth weight exhibited significantly lower MDI and PDI.
- Higher rates of intellectual and psychomotor developmental delay were observed in these groups.
- Complications including hyperbilirubinemia, birth asphyxia, and neonatal respiratory distress syndrome (NRDS) were associated with lower MDI and PDI.
Conclusions:
- Lower gestational age and birth weight are linked to adverse neurodevelopmental outcomes in preterm infants.
- Specific neonatal complications significantly impair cognitive and motor development.
- Findings highlight the importance of monitoring and managing risks in preterm infants.
Objective:
To investigate the neurodevelopmental level of preterm infants at the corrected age of 1 year and the effect of complications on neurodevelopment.
Methods:
The clinical data and follow-up data of hospitalized preterm infants were retrospectively studied. The Bayley Scales of Infant Development was used to assess the neurodevelopmental level. Preterm infants were divided into groups according to gestational age, birth weight, and the presence or absence of complications. The mental development index (MDI) and psychomotor development index (PDI) were compared between groups.
Results:
At the corrected age of 1 year, compared with the late preterm infants, the early preterm infants had significantly lower MDI and PDI (P<0.05) and significantly higher rates of retarded intellectual and psychomotor development (P<0.01). Compared with the normal birth weight group, the low birth weight group had significantly lower MDI and PDI (P<0.01) and significantly higher rates of retarded intellectual and psychomotor development (P<0.01). The preterm infants with hyperbilirubinemia, birth asphyxia or neonatal respiratory distress syndrome (NRDS) had significantly lower MDI and PDI than those without such complications (P<0.05).
Conclusions:
Lower gestational age and birth weight are associated with worse intellectual and psychomotor development in preterm infants. Complications, such as hyperbilirubinemia, birth asphyxia and NRDS, have adverse effects on neurodevelopment of preterm infants.
Related Concept Videos
Neurulation
The Nativist Approach
Language Development
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
Introduction to Developmental Psychology
Piaget's Stage 1 of Cognitive Development
Exploration...

