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Updated: Mar 7, 2026
Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates
Published on: September 6, 2017
Diagnostic yield of ambulatory EEGs in the elderly
Benjamin Tolchin1, Jong Woo Lee1, Milena Pavlova1
1Department of Neurology, The Edward B. Bromfield Epilepsy Program, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Objective:
The diagnostic yield of ambulatory EEG in the elderly is not known. We sought to determine diagnostic yield and identify factors predicting diagnostic findings in this elderly population.
Methods:
We reviewed 156 consecutive 24-72h ambulatory EEGs performed on patients aged 60 or older.
Results:
Of the 156 studies, 58 studies (37%) revealed potentially diagnostic findings: either epileptiform discharges, an epileptic seizure, or a typical nonepileptic event. Focal slowing on routine EEG predicted epileptiform abnormalities on ambulatory EEG with an odds ratio of 4.0 (95% CI 1.7-9.7, p=0.002). Age, the presence of a focal lesion on MRI, and duration of ambulatory EEG failed to predict epileptiform abnormalities on ambulatory EEG. Duration of ambulatory EEG predicted capture of a typical nonepileptic event with an odds ratio of 2.7 (95% CI 1.3-5.7, p=0.009) for every additional day of study duration.
Conclusions:
Focal slowing on routine EEGs may warrant an ambulatory EEG in the setting of diagnostic uncertainty. Longer ambulatory EEGs have a higher yield in capturing patients' typical non-epileptic events, and should be considered in patients where nonepileptic events are a likely diagnostic possibility.
Significance:
These findings offer guidance in the use of ambulatory EEGs in the elderly.
