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Updated: Mar 7, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Granulocytic sarcoma: a rare cause of sciatica
Epaminondas Markos Valsamis1, Thomas Edward Glover2
1Department of Trauma and Orthopaedics, Hinchingbrooke Health Care NHS Trust, Huntingdon, Cambridgeshire, UK.
Abstract:
We describe a case report of a man aged 56 years with a 4-month history of right-sided sciatica-type pain with subclinical disc prolapse evident on MRI. Worsening pain together with the appearance of a tender mass in his right buttock prompted further imaging, which demonstrated an infiltrative mass engulfing the lumbosacral plexus. This was later shown to be a granulocytic sarcoma on biopsy. Intervertebral disc herniation can be an incidental finding and is not always the cause of sciatica.

