Related Experiment Video
Updated: Mar 7, 2026
09:57
Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
3.7K
[PRES: Posterior Reversible Encephalopathy Syndrome]
Kouichirou Okamoto1, Kunio Motohashi, Hidemoto Fujiwara
1Brain Research Institute, Niigata University.
Brain and Nerve = Shinkei Kenkyu No Shinpo
|February 17, 2017
Summary
Posterior reversible encephalopathy syndrome (PRES) causes reversible brain swelling, often in the back of the brain. Early diagnosis and treatment are key for a good outcome, differentiating it from stroke.
Area of Science:
- Neurology
- Radiology
- Internal Medicine
Background:
- Posterior reversible encephalopathy syndrome (PRES) is a neurological condition characterized by reversible vasogenic edema.
- It is associated with various clinical contexts including hypertension, renal failure, and immunosuppression.
Observation:
- Predominantly affects bilateral parieto-occipital regions.
- Brain MRI may reveal intracranial hemorrhage or restricted diffusion mimicking infarction.
- Spinal cord involvement can occur with posterior fossa lesions.
Findings:
- PRES is a clinical syndrome with a generally favorable prognosis.
- Endothelial dysfunction is the primary cause of the brain edema.
- Differentiating PRES from stroke is crucial in neurological emergencies.
Implications:
- Understanding PRES pathophysiology aids early diagnosis and treatment.
- Appropriate therapies can improve clinical course and patient outcomes.
- Accurate differentiation from stroke is vital for timely management.
