Related Experiment Video
Updated: Mar 7, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Intravascular Papillary Endothelial Hyperplasia (Masson's Tumor): Diagnosis the Plastic Surgeon Should Be Aware of
Stefanos Boukovalas1, Rachel Dillard1, Suimin Qiu1
1Division of Plastic Surgery, Department of Surgery, University of Texas Medical Branch, Galveston, Tex.; School of Medicine, University of Texas Medical Branch, Galveston, Tex.; and Department of Surgical Pathology, University of Texas Medical Branch, Galveston, Tex.
Abstract:
Intravascular papillary endothelial hyperplasia (IPEH) or Masson's tumor is a rare benign entity commonly found on the head, neck, and upper extremities. It usually arises within a blood vessel but is considered to be a nonneoplastic reactive process often associated with vascular injury. Typically, IPEHs cause no symptoms and present as slowly growing soft-tissue masses. Given their prevalent location and indolent clinical presentation, the plastic surgeon should be familiar with this rare entity. We are presenting a case of IPEH of the forehead with unusual clinical and pathologic characteristics. Differential diagnosis, special considerations regarding preoperative work-up, and treatment options are discussed.

