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Multiple Brain Abscesses in an Immunocompetent Patient With Factor V Leiden Mutation
Saeed Zubair Zafar1, Najwa Pervin1, Sukesh Manthri1
1Southern Illinois University, Springfield, IL, USA.
Journal of Investigative Medicine High Impact Case Reports
|February 17, 2017
Summary
Multiple brain abscesses are challenging, especially without clear risk factors. This case highlights a rare instance in an immunocompetent patient with Factor V Leiden mutation, suggesting new diagnostic considerations.
Area of Science:
- Neurology
- Infectious Diseases
- Hematology
Background:
- Multiple brain abscesses are typically associated with identifiable predisposing factors.
- Diagnosing brain abscesses in immunocompetent patients without traditional risk factors presents a clinical challenge.
Purpose of the Study:
- To report an unusual case of multiple brain abscesses in an immunocompetent patient.
- To investigate potential risk factors in the absence of conventional causes.
- To explore the association with Factor V Leiden mutation.
Main Methods:
- Case report of a 51-year-old female patient.
- Comprehensive clinical evaluation and diagnostic workup.
- Extensive literature review.
Main Results:
- The patient presented with multiple brain abscesses.
- No conventional predisposing factors for brain abscess were identified.
- The patient had a history of Factor V Leiden mutation and deep vein thrombosis on anticoagulation.
Conclusions:
- This represents the first reported case of multiple brain abscesses in a patient with Factor V Leiden mutation and no other identified risk factors.
- The findings suggest a potential, previously unrecognized association between Factor V Leiden mutation and brain abscess development.
- Further research is warranted to elucidate the potential mechanism of infection in such cases.
