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Updated: Mar 7, 2026
Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Human immunodeficiency virus-negative plasmablastic lymphoma: A case report and literature review
Li Lin1, Xudong Zhang, Meng Dong
1Department of oncology, Institute of Clinical Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou Henan Department of Medical Oncology, Fujian Provincial Hospital, Fuzhou, China.
Rationale:
Plasmablastic lymphoma (PBL) is a rare subtype of human immunodeficiency virus (HIV)-related non-Hodgkin's lymphoma that predominantly manifests in the oral cavity.
Patient Concerns:
Three cases of HIV-negative PBL were reported.
Diagnoses:
HIV-negative PBL INTERVENTIONS:: The patient had undergone chemotherapy.
Outcomes:
Clinical outcomes were very poor in Cases 1 and 3; Case 2, whose diagnosis suggested no bone marrow involvement, is still alive.
Lessons Subsections:
These cases served to broaden the reported clinical spectrum of HIV-negative PBL. Clinicians and pathologists need to be familiar with lymphoma in the identified extra-oral PBL variation and there levant differential diagnosis procedures for this particular disease.
