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A new approach for EPR detection of hydroxyl radicals by reaction with sterically hindered cyclic amines and oxygen
I Rosenthal1, C M Krishna, G C Yang
1Division of Contaminant Chemistry, Center for Food Safety and Applied Nutrition, Washington, DC 20204.
FEBS Letters
|September 28, 1987
Abstract:
Sterically hindered cyclic amines react with hydroxyl radicals in the presence of oxygen to yield stable nitroxide radicals which can be detected by EPR. This reaction provides a nonconventional spin-trapping tool for detection of hydroxyl radicals.