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Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
Percutaneous Transcatheter Therapies for the Management of Left Ventricular Assist Device Complications
Rohan J Kalathiya, Jonathan Grinstein, Nir Uriel
1The University of Chicago Medicine, 5841 S. Maryland Ave, MC 6080, Chicago, IL 60637 USA. ashah@bsd.uchicago.edu.
Insights
Continuous-flow left ventricular assist devices (LVADs) are increasingly used for heart failure. This review discusses mechanical complications and emerging transcatheter therapies for LVAD support.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Medical Devices
Background:
- Heart failure is a global epidemic, increasing demand for advanced therapies.
- Continuous-flow left ventricular assist devices (LVADs) are vital for managing advanced heart failure.
- Limited organ donor availability has extended the use of LVADs for destination therapy.
Purpose of the Study:
- To review mechanical complications associated with left ventricular assist device (LVAD) therapy.
- To discuss the role of interventional transcatheter therapies in managing these complications.
Main Methods:
- This article reviews current literature on LVAD-related mechanical complications.
- It examines the application of transcatheter interventions as alternatives to surgical repair.
Main Results:
- Prolonged LVAD support is linked to mechanical issues like thrombosis, aortic insufficiency, and graft stenosis.
- Transcatheter therapies offer less invasive options for managing these complications.
- Surgical repair, while effective, carries significant operative risks for some patients.
Conclusions:
- Mechanical complications are a growing concern with increased LVAD utilization.
- Transcatheter interventions represent a promising alternative for managing LVAD complications.
- Further research is needed to optimize transcatheter approaches for LVAD patients.
Abstract:
Heart failure is a growing epidemic in the United States and throughout the world. The utilization of continuous-flow left ventricular assist devices (LVADs) has greatly increased over the last decade. In addition, a limited supply of organ donors has led to a rise in the use, and duration, of LVADs for destination therapy. The increased use of LVAD therapy has led to the observation of mechanical complications such as device thrombosis, de novo aortic insufficiency, and outflow graft stenosis, all of which are associated with prolonged LVAD support. Surgical repair for these complications remains the therapy of choice; however, surgery may be associated with high operative risk in some patients. The purpose of this article is to discuss mechanical complications associated with LVAD therapy and interventional transcatheter therapies that have been used to solve these increasingly complex problems.
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