Percutaneous Transcatheter Therapies for the Management of Left Ventricular Assist Device Complications

Rohan J Kalathiya, Jonathan Grinstein, Nir Uriel

  • 1The University of Chicago Medicine, 5841 S. Maryland Ave, MC 6080, Chicago, IL 60637 USA. ashah@bsd.uchicago.edu.

Insights

Continuous-flow left ventricular assist devices (LVADs) are increasingly used for heart failure. This review discusses mechanical complications and emerging transcatheter therapies for LVAD support.

Area of Science:

  • Cardiology
  • Cardiovascular Surgery
  • Medical Devices

Background:

  • Heart failure is a global epidemic, increasing demand for advanced therapies.
  • Continuous-flow left ventricular assist devices (LVADs) are vital for managing advanced heart failure.
  • Limited organ donor availability has extended the use of LVADs for destination therapy.

Purpose of the Study:

  • To review mechanical complications associated with left ventricular assist device (LVAD) therapy.
  • To discuss the role of interventional transcatheter therapies in managing these complications.

Main Methods:

  • This article reviews current literature on LVAD-related mechanical complications.
  • It examines the application of transcatheter interventions as alternatives to surgical repair.

Main Results:

  • Prolonged LVAD support is linked to mechanical issues like thrombosis, aortic insufficiency, and graft stenosis.
  • Transcatheter therapies offer less invasive options for managing these complications.
  • Surgical repair, while effective, carries significant operative risks for some patients.

Conclusions:

  • Mechanical complications are a growing concern with increased LVAD utilization.
  • Transcatheter interventions represent a promising alternative for managing LVAD complications.
  • Further research is needed to optimize transcatheter approaches for LVAD patients.

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