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Updated: Jul 21, 2026

Two Peeling Methods for the Isolation of Photoreceptor Cell Compartments in the Mouse Retina for Protein Analysis
Published on: December 7, 2021
Measurements of the stabilities of isolated retinal chromophores
L Musbat1, M Nihamkin1, Y Toker1
1Department of Physics and Institute of Nanotechnology, Bar-Ilan University, Ramat-Gan 5290002, Israel.
Abstract:
The barrier energies for isomerization and fragmentation were measured for a series of retinal chromophore derivatives using a tandem ion mobility spectrometry approach. These measurements allow us to quantify the effect of charge delocalization on the rigidity of chromophores. We find that the role of the methyl group on the C13 position is pivotal regarding the ground state dynamics of the chromophore. Additionally, a correlation between quasi-equilibrium isomer distribution and fragmentation pathways is observed.
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