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Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
Arterial access-site complications after use of a vascular closure device related to puncture height
Benjamin Sartorius1, Michael Behnes2, Melike Ünsal1
1First Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Insights
This study found no significant differences in bleeding complications after percutaneous coronary intervention (PCI) when using vascular closure devices (VCDs) based on femoral arterial puncture height. Puncture location did not impact major bleeding events.
Area of Science:
- Cardiology
- Vascular Surgery
- Interventional Cardiology
Background:
- Percutaneous coronary intervention (PCI) commonly uses femoral arterial access.
- Vascular closure devices (VCDs) are frequently employed to manage arterial access sites.
- Complications related to femoral access, such as bleeding, are a concern.
Purpose of the Study:
- To investigate the relationship between the height of femoral arterial puncture and access-site complications.
- To evaluate the impact of vascular closure device (VCD) use on bleeding complications in relation to puncture site.
- To analyze bleeding event differences based on common femoral artery (CFA), bifurcation, or lower puncture sites.
Main Methods:
- A subgroup of the FERARI study involving femoral arterial access and pre-VCD inguinal angiography was analyzed.
- Inguinal angiographies were reviewed by cardiologists to determine puncture height.
- Bleeding complications within 30 days post-PCI were documented and categorized using BARC, TIMI, GUSTO, and FERARI classifications.
Main Results:
- Common femoral artery (CFA) access occurred in 41%, bifurcation in 39%, and low puncture in 20% of patients.
- No significant differences in PCI indications, procedural data, or anticoagulation were noted based on puncture height.
- While CFA puncture showed numerically higher bleeding (62%) compared to bifurcation (41%), this was not statistically significant (p=0.059).
Conclusions:
- Femoral arterial puncture height and the use of VCDs did not significantly influence bleeding complications after PCI.
- No significant differences in bleeding events or other vascular endpoints were observed concerning puncture height.
- The study suggests that puncture site location may not be a critical factor for bleeding risk when using VCDs in PCI.
Background:
To analyze differences of access-site complications related to the height of femoral arterial puncture and the use of a vascular closure device (VCD) following percutaneous coronary intervention (PCI).
Methods:
A subgroup of the FERARI study being treated by femoral arterial access and valuable inguinal angiography before implantation of a VCD were included. Inguinal angiographies were systematically reviewed by two independent cardiologists to determine the correct height of femoral arterial puncture. Bleeding complications were documented within 30 days after PCI and were categorized according to BARC, TIMI, GUSTO and FERARI classifications.
Results:
Femoral access point imaging was available in 95 patients compared to 105 patients without. The common femoral artery (CFA) was the most accessed artery in 41%, followed by the femoral arterial bifurcation (39%) and lower access sites distally from the femoral arterial bifurcation (low puncture: 20%). No differences were observed regarding indication of PCI, procedural data and anticoagulation therapies in relation to the heights of femoral arterial access (p > 0.05). Despite using VCD, arterial puncture at the CFA resulted in numerically highest numbers of overall bleedings (62%) compared to femoral arterial bifurcation (41%) (p = 0.059). 58% of bleedings occurred after arterial puncture below the femoral bifurcation (low puncture). Though no significant differences of bleedings regarding classifications of BARC, GUSTO, TIMI and FERARI as well as other vascular endpoints were observed regarding puncture height.
Conclusions:
The present analysis demonstrates no significant differences of bleeding complications in relation to the height of femoral arterial puncture and subsequent use of a VCD.
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