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Helicobacter pylori: The Past, Present, and Future in Management
Amrit K Kamboj1, Thomas G Cotter1, Amy S Oxentenko2
1Department of Internal Medicine, Mayo Clinic, Rochester, MN.
Mayo Clinic Proceedings
|February 18, 2017
Summary
This review simplifies Helicobacter pylori (H pylori) diagnosis and treatment for primary care. It covers H pylori epidemiology, pathogenesis, and evidence-based testing and therapy options for better patient outcomes.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Microbiology
Background:
- Helicobacter pylori (H pylori) is a prevalent bacterial pathogen causing significant global gastrointestinal illness.
- Managing H pylori infections presents clinical challenges due to diverse diagnostic and therapeutic strategies.
Purpose of the Study:
- To systematically review H pylori epidemiology and pathogenesis.
- To present a simplified, primary care-focused approach to diagnosing and treating H pylori infections.
Main Methods:
- Systematic literature review of H pylori epidemiology and pathogenesis.
- Synthesis of diagnostic and therapeutic options for primary care application.
Main Results:
- Established indications for H pylori testing.
- Identified key noninvasive and invasive diagnostic methods.
- Outlined advantages and disadvantages of various H pylori treatment regimens.
Conclusions:
- A simplified approach to H pylori diagnosis and treatment is feasible for primary care settings.
- Understanding H pylori epidemiology and pathogenesis aids clinical decision-making.
- Evidence-based guidance on testing and treatment improves management of H pylori infections.
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