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Left ventricular non-compaction in a patient with ankylosing.
Mehrnoush Toufan1, Leili Pourafkari2, Nader D Nader3
1Cardiovascular Research Center, Tabriz University of Medical Sciences,Tabriz, Iran.
Journal of Cardiovascular and Thoracic Research
|February 18, 2017
Summary
This case highlights a rare cardiac complication in ankylosing spondylitis (AS). We report an association between AS and non-compaction cardiomyopathy, a condition affecting heart muscle function.
Area of Science:
- Cardiology
- Rheumatology
- Genetics
Background:
- Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the axial skeleton.
- Cardiac involvement in AS commonly includes aortic insufficiency and conduction abnormalities.
- Myocardial involvement, such as dilated or restrictive cardiomyopathy, is less common.
Observation:
- A 58-year-old male with a history of HLA-B27 positive AS presented with fatigue and dyspnea.
- Echocardiography revealed left ventricular dysfunction, aortic insufficiency, and left ventricular non-compaction (LVNC).
Findings:
- The patient exhibited severe eccentric aortic insufficiency and left ventricular enlargement.
- The echocardiographic findings demonstrated left ventricular non-compaction cardiomyopathy in conjunction with AS.
Implications:
- This case underscores the potential for rare cardiac manifestations in AS patients.
- It suggests that LVNC should be considered in the differential diagnosis of cardiomyopathy in AS.
- Further research is needed to elucidate the mechanisms linking AS and LVNC.
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