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Updated: Mar 7, 2026

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
Anesthetic considerations for pediatric electroconvulsive therapy
Andrew D Franklin1, Jenna H Sobey1, Eric T Stickles1
1Department of Anesthesiology, Division of Pediatric Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.
Insights
Pediatric electroconvulsive therapy (ECT) is increasingly used for various psychiatric conditions and refractory status epilepticus. Anesthesiologists play a key role, carefully selecting agents to optimize seizure quality and patient safety.
Area of Science:
- Pediatric Anesthesiology
- Child and Adolescent Psychiatry
- Neurology
Background:
- Electroconvulsive therapy (ECT) is increasingly utilized for pediatric psychiatric disorders.
- Indications include refractory depression, bipolar disorder, schizophrenia, catatonia, autism, and status epilepticus.
- Anesthesiologists are integral to managing this vulnerable population.
Purpose of the Study:
- To review anesthetic considerations for pediatric electroconvulsive therapy.
- To discuss anesthetic agents and their impact on seizure quality.
- To highlight the importance of multidisciplinary team communication.
Main Methods:
- Review of anesthetic techniques and agents for pediatric ECT.
- Discussion of preoperative anxiolysis and induction agents.
- Consideration of anesthetic effects on evoked seizure parameters.
Main Results:
- Dexmedetomidine is a preferred preoperative anxiolytic; oral benzodiazepines are contraindicated.
- Methohexital is the traditional induction agent, with ketamine, propofol, and sevoflurane as alternatives.
- Anesthetic choices must balance patient safety with optimal seizure induction.
Conclusions:
- Careful anesthetic planning is crucial for successful pediatric ECT.
- Multidisciplinary communication minimizes risks and maximizes therapeutic benefits.
- Optimizing anesthetic management enhances the efficacy and safety of pediatric ECT.
Abstract:
Electroconvulsive therapy is being used more frequently in the treatment of many chronic and acute psychiatric illnesses in children. The most common psychiatric indications for pediatric electroconvulsive therapy are refractory depression, bipolar disorder, schizophrenia, catatonia, and autism. In addition, a relatively new indication is the treatment of pediatric refractory status epilepticus. The anesthesiologist may be called upon to assist in the care of this challenging and vulnerable patient population. Unique factors for pediatric electroconvulsive therapy include the potential need for preoperative anxiolytic and inhalational induction of anesthesia, which must be weighed against the detrimental effects of anesthetic agents on the evoked seizure quality required for a successful treatment. Dexmedetomidine is likely the most appropriate preoperative anxiolytic as oral benzodiazepines are relatively contraindicated. Methohexital, though becoming less available at many institutions, remains the gold standard for induction of anesthesia for pediatric electroconvulsive therapy though ketamine, propofol, and sevoflurane are becoming increasingly viable options. Proper planning and communication between the multidisciplinary teams involved in the care of children presenting for electroconvulsive therapy treatments is vital to mitigating risks and achieving the greatest therapeutic benefit.
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