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Related Concept Videos

Papillary Dermis01:11

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Dermatoglyphics in Vitiligo.

K C Verma, V K Jain

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    Summary
    This summary is machine-generated.

    Dermatoglyphic patterns in vitiligo patients showed some differences in finger loops and arches between sexes, but these variations were not statistically significant. Total ridge count remained unchanged in vitiligo cases compared to controls.

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    Area of Science:

    • Dermatoglyphics
    • Dermatology
    • Genetics

    Background:

    • Vitiligo is a complex depigmentation disorder.
    • Dermatoglyphics, the study of skin patterns, may offer insights into genetic predispositions.
    • Previous research on dermatoglyphic patterns in vitiligo has yielded varied results.

    Purpose of the Study:

    • To investigate dermatoglyphic patterns and total ridge count in vitiligo patients.
    • To compare dermatoglyphic features between vitiligo cases and healthy controls.
    • To explore potential sex-specific differences in dermatoglyphic patterns associated with vitiligo.

    Main Methods:

    • A case-control study involving 80 participants (40 vitiligo cases, 40 controls).
    • Analysis of dermatoglyphic patterns, including finger loops and arches.
    • Calculation of total ridge count for each participant.

    Main Results:

    • In males with vitiligo, an increased incidence of radial loops on the 2nd finger and arches was observed.
    • In females with vitiligo, an increased incidence of ulnar loops on the 3rd digit was noted.
    • No statistically significant differences in dermatoglyphic patterns were found between vitiligo cases and controls.
    • Total ridge count showed no significant change in vitiligo cases.

    Conclusions:

    • While some sex-specific variations in dermatoglyphic patterns were observed in vitiligo, they were not statistically significant.
    • Dermatoglyphic patterns and total ridge count do not appear to be significantly altered in vitiligo patients.
    • Further research with larger sample sizes may be warranted to explore subtle associations.