[Correlation of heart rate variability with SYNTAX II on chronic angina]

Tatiana Chantal Castro-de la Torre1, Norma Amador-Licona, Enrique Bernal-Ruíz

  • 1Servicio de Cardiología, Hospital General de Zona 2, Instituto Mexicano del Seguro Social, Irapuato, Guanajuato, México. enriquebernalmd@yahoo.com.mx.

Insights

Heart rate variability (HRV) did not correlate with coronary artery disease severity in chronic angina patients. However, low HRV was linked to increased ventricular tachycardia events, indicating a potential risk factor.

Area of Science:

  • Cardiology
  • Clinical Research

Background:

  • Heart rate variability (HRV) is a known prognostic indicator for cardiovascular risk.
  • The relationship between HRV and coronary artery disease (CAD) severity in chronic angina patients remains unclear.
  • Investigating HRV's correlation with CAD severity is crucial for risk stratification in stable ischemic heart disease.

Purpose of the Study:

  • To determine the correlation between heart rate variability (HRV) and the SYNTAX II score in patients with chronic angina.
  • To assess if HRV can predict the severity of coronary artery disease in this population.
  • To explore the prognostic value of HRV in chronic angina.

Main Methods:

  • A cross-sectional study involving adult patients with stable angina requiring coronary angiography.
  • HRV was assessed using 24-hour Holter ECG, and coronary severity was quantified using the SYNTAX II score.
  • Pearson's correlation test was employed to analyze the relationship between HRV parameters (SDNN, RMSSD) and the SYNTAX II score.

Main Results:

  • No significant correlation was found between HRV parameters (SDNN, RMSSD) and the SYNTAX II score in the study cohort.
  • A high prevalence of decreased HRV was observed: 73.77% had low SDNN and 13.11% had low RMSSD.
  • Patients with low SDNN exhibited a higher incidence of ventricular tachycardia compared to those with normal SDNN (15.5% vs. 0.0%, p=0.04).

Conclusions:

  • HRV does not correlate with the severity of coronary artery disease in patients with stable chronic ischemic heart disease.
  • Low HRV, specifically reduced SDNN, is associated with an increased risk of ventricular tachycardia in this patient group.
  • These findings suggest that while HRV may not reflect CAD complexity, it could serve as a marker for arrhythmia risk in chronic angina.
Abstract

Related Concept Videos

Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
506
Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
316
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
355
Correlation between ECG and Cardiac Cycle01:25

Correlation between ECG and Cardiac Cycle

The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
13.8K
Factors Influencing Heart Rate01:30

Factors Influencing Heart Rate

The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
7.1K
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
505