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[Correlation of heart rate variability with SYNTAX II on chronic angina]
Tatiana Chantal Castro-de la Torre1, Norma Amador-Licona, Enrique Bernal-Ruíz
1Servicio de Cardiología, Hospital General de Zona 2, Instituto Mexicano del Seguro Social, Irapuato, Guanajuato, México. enriquebernalmd@yahoo.com.mx.
Insights
Heart rate variability (HRV) did not correlate with coronary artery disease severity in chronic angina patients. However, low HRV was linked to increased ventricular tachycardia events, indicating a potential risk factor.
Area of Science:
- Cardiology
- Clinical Research
Background:
- Heart rate variability (HRV) is a known prognostic indicator for cardiovascular risk.
- The relationship between HRV and coronary artery disease (CAD) severity in chronic angina patients remains unclear.
- Investigating HRV's correlation with CAD severity is crucial for risk stratification in stable ischemic heart disease.
Purpose of the Study:
- To determine the correlation between heart rate variability (HRV) and the SYNTAX II score in patients with chronic angina.
- To assess if HRV can predict the severity of coronary artery disease in this population.
- To explore the prognostic value of HRV in chronic angina.
Main Methods:
- A cross-sectional study involving adult patients with stable angina requiring coronary angiography.
- HRV was assessed using 24-hour Holter ECG, and coronary severity was quantified using the SYNTAX II score.
- Pearson's correlation test was employed to analyze the relationship between HRV parameters (SDNN, RMSSD) and the SYNTAX II score.
Main Results:
- No significant correlation was found between HRV parameters (SDNN, RMSSD) and the SYNTAX II score in the study cohort.
- A high prevalence of decreased HRV was observed: 73.77% had low SDNN and 13.11% had low RMSSD.
- Patients with low SDNN exhibited a higher incidence of ventricular tachycardia compared to those with normal SDNN (15.5% vs. 0.0%, p=0.04).
Conclusions:
- HRV does not correlate with the severity of coronary artery disease in patients with stable chronic ischemic heart disease.
- Low HRV, specifically reduced SDNN, is associated with an increased risk of ventricular tachycardia in this patient group.
- These findings suggest that while HRV may not reflect CAD complexity, it could serve as a marker for arrhythmia risk in chronic angina.
Background:
The heart rate variability (HRV) is a prognostic value of cardiovascular risk. It is unknown the correlation between HRV and coronary severity on patients with chronic angina. The objective was to determine the correlation between HRV and the SYNTAX II score in chronic angina.
Methods:
Cross-sectional study in patients of 18 years or older with stable angina and indication of coronary angiography who went to a third level center. The SYNTAX II score was established by using coronary angiography, while HRV was obtained by a 24-hour Holter ECG. The correlation between SYNTAX II and HRV was performed with Pearson's test. Values of SDNN < 100 ms and RMSSD < 15 ms were considered risk factors.
Results:
61 patients were included. 45 had a decreased value of SDNN (73.77%) and eight had a decreased value of RMSSD (13.11%). There was no correlation between HRV and SYNTAX II score. There were more events of ventricular tachycardia in the group of patients with low SDNN than in those with normal SDNN (15.5% vs. 0.0%; p = 0.04).
Conclusions:
There was no correlation between HRV and the severity of coronary artery disease in stable chronic ischemic heart disease. However, those patients with low HRV showed more events of ventricular tachycardia.
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