Related Experiment Video
Updated: Oct 7, 2026

Engineered Vascularized Muscle Flap
Published on: January 11, 2016
Trends in Coronary Revascularization and Ischemic Heart Disease-Related Mortality in Israel
Orit Blumenfeld1, Wasef Na'amnih2, Ayelet Shapira-Daniels3
1Israel Centers for Disease Control, Ministry of Health, Ramat Gan, Israel orit.blumenfeld@moh.health.gov.il.
Insights
Percutaneous coronary angioplasty (PCI) volume initially rose then fell, while coronary artery bypass grafting (CABG) significantly declined in Israel. Despite these shifts, procedural mortality remained stable, and ischemic heart disease mortality decreased substantially.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Background:
- Investigated national trends in coronary revascularization procedures and ischemic heart disease mortality in Israel.
- Examined percutaneous coronary angioplasty (PCI) and coronary artery bypass grafting (CABG) volumes and outcomes.
- Assessed ischemic heart disease-related mortality rates.
Purpose of the Study:
- To analyze national trends in the volume and outcomes of PCI and CABG in Israel from 2002 to 2014.
- To evaluate changes in procedural mortality and ischemic heart disease-related mortality over the study period.
- To identify shifts in the utilization of different revascularization strategies.
Main Methods:
- Linked five Israeli national databases, including specialized PCI and CABG registries.
- Utilized International Classification of Diseases codes for data extraction.
- Analyzed trends using linear regression with a Poisson distribution assumption.
Main Results:
- Total revascularization procedures exceeded 298,000.
- PCI volume increased initially then decreased; CABG volume saw a significant decline of 59%.
- In-hospital procedural mortality remained stable for both PCI and CABG, while ischemic heart disease mortality decreased by 46%.
Conclusions:
- Observed a significant shift in the type and volume of coronary revascularization procedures in Israel.
- Noted a substantial reduction in ischemic heart disease-related mortality.
- The underlying reasons for these observed changes require further investigation.
Background:
We investigated national trends in volume and outcomes of percutaneous coronary angioplasty (PCI), coronary artery bypass grafting (CABG), and ischemic heart disease-related mortality in Israel.
Methods And Results:
Using International Classification of Diseases 9th and 10th revision codes, we linked 5 Israeli national databases, including the Israel Center for Disease Control National PCI and CABG Registries, the Ministry of Health Hospitalization Report, the Center of Bureau of Statistics, and the Ministry of Interior Mortality Report, to assess the annual PCI and CABG volume, procedural mortality, comorbidities, and ischemic heart disease-related mortality between 2002 and 2014. Trends over time were analyzed using linear regression, assuming a Poisson distribution. A total of 298 390 revascularization procedures (PCI: 255 724, CABG: 42 666) were performed during the study period. PCI volume increased by 9% from 2002 to 2008 (387.4/100 000 to 423.2/100 000), steadily decreasing by 10.5% to 378.5/100 000 in 2014 (P=0.70 for the trend). CABG volume decreased by 59% (109.0/100 000 to 45.2/100 000) from 2002 to 2013, leveling at 46.4/100 000 (P<0.0001). PCI/CABG ratio increased from 3.6 in 2002 to 8.5 in 2013, slightly decreasing to 8.2 by 2014 (P<0.0001). In-hospital procedural mortality remained stable (PCI: 1.2-1.6%, P=0.34, CABG: 3.7-4.4%, P=0.29) despite a significant change in patient clinical profile. During the course of the study, ischemic heart disease-related mortality decreased by 46% (84.6-46/100 000, P<0.001).
Conclusions:
We observed a dramatic change in coronary revascularization procedures type and volume, and a marked decrease in ischemic heart disease-related mortality in Israel. The reasons for the observed changes remain unclear and need to be further investigated.
Related Concept Videos
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Coronary Artery Disease I: Introduction
Coronary Artery Disease II: Pathophysiology
Coronary Artery Disease III: Clinical Manifestations
Coronary Artery Disease IV: Preventive Measures
Acute Coronary Syndrome III: Diagnostic Studies

