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Updated: Mar 7, 2026

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
Sciatic neuropathy due to popliteal fossa nerve block
Adam Aubuchon1, W David Arnold1,2,3, Anna Bracewell4
1Department of Neurology, Division of Neuromuscular Medicine, The Ohio State University Wexner Medical Center, 395 West 12th Avenue, Columbus, Ohio, 43210, USA.
Popliteal nerve block (PNB) is an increasingly recognized cause of sciatic neuropathy. This study found PNB to be the third most common cause of sciatic neuropathy, highlighting its importance in post-surgical diagnosis.
Area of Science:
- Neurology
- Anesthesiology
- Surgical Complications
Background:
- Sciatic neuropathy is a known complication of regional anesthesia.
- Popliteal nerve block (PNB) is frequently used for lower extremity surgeries.
- The incidence of PNB-related sciatic neuropathy is considered uncommon but requires further investigation.
Observation:
- A retrospective review of 45 sciatic neuropathy cases was conducted over a 5-year period.
- Common causes included compression, trauma, fractures, and hip arthroplasty (60%).
- Popliteal nerve block (PNB) emerged as the third most frequent etiology (16%).
Findings:
- Popliteal nerve block (PNB) is a more common cause of sciatic neuropathy than previously thought.
- PNB accounted for 16% of sciatic neuropathy cases in this series.
- The study identified PNB as a significant etiology in post-operative sciatic neuropathy.
Implications:
- Electromyographers should consider PNB in the differential diagnosis of sciatic neuropathy, especially after surgery.
- Increased awareness of PNB as a cause of sciatic neuropathy is crucial for accurate diagnosis and patient management.
- This finding underscores the importance of detailed patient history, including anesthetic procedures, in evaluating neuropathic conditions.
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